Safety

Investigation of cutaneous safety is a critical component of topical product development for both pharmaceuticals and cosmetics.

At bioskin® we are experienced in the design and conduct of the entire spectra of cutaneous safety studies and offer a battery of safety tests required for assessment of products which are applied locally and exert their effects at the site of application. 
In addition we conduct trials evaluating systemic safety (e.g. ECGs, clinical chemical parameters, systemic absorption) and histological / immunohistochemical effects.

Designs for evaluation of safety include:

  • Dermal irritation (diverse models)
  • Ocular tolerability
  • Sensitization potential
  • Phototoxic and photosensitization potential
  • Systemic absorption and pharmacokinetics
  • Skin atrophogenic potential
  • Dermal tolerability and sensitization potential of transdermals