Efficacy testing / Proof-of-Concept trials
A core expertise at bioskin® is development of innovative test models for evaluation of efficacy of topical drugs and medical devices. In these models biophysical measurement methods can often be used to deliver objective data to support traditional clinical endpoints. We customize designs for efficacy trials depending on the indication and product profile.
Routine in-house Proof-of-Concept / efficacy trials include:
- Psoriasis plaque test (for anti-psoriatics, also for screening of generic formulations)
- UV-induced erythema model (for anti-inflammatories)
- Pain model (for topical analgesics, anti-inflammatories)
- Vasoconstrictor assay (for corticosteroids)
- Superficial wound healing (abrasion model, suction blister model for re-epithelization)
- Expanded flora test (for anti-bacterials)
- Acne/rosacea
- Alopecia/hair growth
- Atopic dermatitis
- Onychomychosis
- Psoriasis
- Tinea pedis
